E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Incidence of neonatal sepsis in tertiary care hospital: An overview

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani.

Cited by (2)

Abstract
Background: Neonatal sepsis is one of the commonest causes of neonatal mortality in the developing world.

Aims & Objective: To determine the bacteriological profile of neonatal septicaemia, their antibacterial susceptibility pattern (AST) and production of extended spectrun β-lactamase (ESBL) by gram negative bacteria.

Material and Methods: Blood culture specimens were collected from 238 neonates. Identification of organisms, their AST, methicillin resistant Staphylococcus aureus (MRSA) and ESBL detection was done.

Results: Gram negative bacteria were more frequently isolated than gram positive bacteria. The gram positive bacteria were highly resistant to penicillin. Vancomycin and amoxyclav exhibited good activity against both Staphylococcus aureus and coagulase negative Staphylococcus. Gram negative bacteria also exhibited high resistance to the commonly prescribed group of drugs such as penicillins, cephalosporins and aminoglycosides. Out of the total 16 isolates of S.aureus, 31.25% were MRSA. ESBL production was seen in 52.9% of Escherichia coli and 50% of Klebsiella pneumoniae.

Conclusion: E. coli and S. aureus were the most common bacteria associated with neonatal sepsis. Gram negative bacteria were isolated predominantly and many of them were resistant to several groups of drugs. Also high resistance was seen to third generation cephalosporins in case of E. coli and K. pneumoniae due to ESBL production.

Key words: Antibiotic Susceptibility Pattern; Extended Spectrum β-Lactamases (ESBL); Methicillin Resistant Staphylococcus Aureus (MRSA); Neonatal Sepsis; Premature Rupture of Membrane (PROM)


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. Incidence of neonatal sepsis in tertiary care hospital: An overview. Int J Med Sci Public Health. 2013; 2(3): 548-552. doi:10.5455/ijmsph.2013.090320131


Web Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. Incidence of neonatal sepsis in tertiary care hospital: An overview. http://www.ijmsph.com/?mno=34358 [Access: August 24, 2019]. doi:10.5455/ijmsph.2013.090320131


AMA (American Medical Association) Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. Incidence of neonatal sepsis in tertiary care hospital: An overview. Int J Med Sci Public Health. 2013; 2(3): 548-552. doi:10.5455/ijmsph.2013.090320131



Vancouver/ICMJE Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. Incidence of neonatal sepsis in tertiary care hospital: An overview. Int J Med Sci Public Health. (2013), [cited August 24, 2019]; 2(3): 548-552. doi:10.5455/ijmsph.2013.090320131



Harvard Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani (2013) Incidence of neonatal sepsis in tertiary care hospital: An overview. Int J Med Sci Public Health, 2 (3), 548-552. doi:10.5455/ijmsph.2013.090320131



Turabian Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. 2013. Incidence of neonatal sepsis in tertiary care hospital: An overview. International Journal of Medical Science and Public Health, 2 (3), 548-552. doi:10.5455/ijmsph.2013.090320131



Chicago Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. "Incidence of neonatal sepsis in tertiary care hospital: An overview." International Journal of Medical Science and Public Health 2 (2013), 548-552. doi:10.5455/ijmsph.2013.090320131



MLA (The Modern Language Association) Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani. "Incidence of neonatal sepsis in tertiary care hospital: An overview." International Journal of Medical Science and Public Health 2.3 (2013), 548-552. Print. doi:10.5455/ijmsph.2013.090320131



APA (American Psychological Association) Style

Shashi Gandhi, KP Ranjan, Neelima Ranjan, Neha Sapre, Mahendra Masani (2013) Incidence of neonatal sepsis in tertiary care hospital: An overview. International Journal of Medical Science and Public Health, 2 (3), 548-552. doi:10.5455/ijmsph.2013.090320131





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