E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta.

Cited by (1)

Abstract
Background: Dengue fever, the most common arbo viral illness transmitted worldwide. Dengue infection in adolescents and adults is also a potential hazard in endemic areas, especially South-east Asia.

Objectives: The present study was done to evaluate the magnitude of dengue death and its predictor factors in a tertiary care hospital of Kolkata.

Materials & Methods: This observational cross sectional study was conducted at a tertiary care centre of Kolkata over 1 year period with 77 patients with a diagnosis of dengue fever based on the serology positive for dengue IgM with fulfilling the inclusion and exclusion criteria. The data were collected on predesigned questionnaire which include gender, clinical findings, complications and laboratory test.Baseline laboratory tests obtained were complete blood count (CBC), partial thromboplastin time (PTT), serum glutamine pyruvate transaminase (SGPT),SGOT, bilirubin, urea, creatinine and IgM. SPSS 16.0 version was used for statistical analysis.

Results: Dengue mortality rate was 28.57% in this study. Among 5 lab parameters chosen i.e.leukopenia, bilirubin>6mg/dl, thrombocytopenia, altered PT/APTT, enzyme>4 fold rise,raised urea/cr ; On multivariate logistic regression analysis hyperbilirubinemia(>6 mg/dl)was statistically significant predictor for mortality(as p value<0.05).

Conclusion: The laboratory parameters could predict the dengue mortality, so proper emphasis should be given to address the situation.

Key words: Dengue infection, Mortality, Predictors.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ranadip Chowdhury
Articles by Koushik Pan
Articles by Anup Sarkar
Articles by Subrata Chakrabarti
Articles by Tanmay Samanta
on Google
on Google Scholar
Article Statistics
 Viewed: 4596
Downloaded: 1023
Cited: 1


REFERENCES
1. Karamchandani PV. Dengue group of fevers in India. Lancet. 1946;1:92 [DOI via Crossref]   
2. Chareonsook O, Foy HM, Teeraratkul A, Silarug N. Changing epidemiology of dengue hemorrhagic fever in Thailand. Epidemiol Infect. 1999;122:161&#8211;6.
3. Pongsumpun P, Yoksan S, Tan IM. A comparison of the age distributions in the dengue hemorrhagic fever epidemics in Santiago de Cuba (1997) and Thailand (1998). Southeast Asian J Trop Med Public Health. 2002;33:255&#8211;8.
4. Kularatne SA, Gawarammana IB, Kumarasiri PR. Epidemiology, clinical features, laboratory investigations and early diagnosis of dengue fever in adults: a descriptive study in Sri Lanka. Southeast Asian J Trop Med Public Health. 2005;36:686&#8211;92.
5. Annual Epidemiological Surveillance Report: Thailand 2012
6. Tantawichien T, Thisyakorn U, Pisarnpong A, Israsena S, Suwangool P. Dengue fever and dengue hemorrhagic fever in adults. The First International Conference on Dengue and Dengue Hemorrhagic fever, Chiang Mai, Thailand, 20&#8211;24 November 2000. Abst. 16&#8211;17
7. Jelinek T. Dengue fever in international travelers. Clin Infect Dis. 2000;31:144&#8211;7.
8. O'Brien D, Tobin S, Brown GV, Torresi J. Fever in returned travelers: review of hospital admissions for a 3-year period. Clin Infect Dis. 2001;33: 603&#8211;9.
9. Pongsumpun P, Patanarapelert K, Sriprom M, Varamit S, Tang IM. Infection risk to travelers going to dengue fever endemic regions. Southeast Asian J Trop Med Public Health. 2004;35:155&#8211;9.
10. Stephan C, Allwinn R, Brodt HR, Knupp B, Preiser W, Just-Nubling G. Travel-acquired dengue infection: clinical spectrum and diagnostic aspects. Infection. 2002;30:225&#8211;8
11. Anderson KB, Chunsuttiwat S, Nisalak A, Mammen MP, Libraty DH, Rothman AL et al. Burden of symptomatic dengue infection in children at primary school in Thailand: a prospective study. Lancet 2007;369: 1452&#8211;1459.
12. Suaya J, Shepard D, Armien B, Caram M, Castillo L, Chantha N et al. Multi-country study of costs of dengue among ambulatory and hospitalized patients. Am J Trop Med Hyg 2007;77: 55.
13. Clark DV, Mammen MP, Jr., Nisalak A, Puthimethee V, Endy TP. Economic impact of dengue fever/dengue hemorrhagic fever in Thailand at the family and population levels. Am J Trop Med Hyg 2005;72: 786&#8211;791.
14. Meltzer MI, Rigau-Perez JG, Clark GG, Reiter P, Gubler DJ. Using disability-adjusted life years to assess the economic impact of dengue in Puerto Rico: 1984&#8211;1994. Am J Trop Med Hyg 1998;59: 265&#8211;271.
15. Suaya JA, Shepard DS, Siqueira JB, Martelli CT, Lum LC S, Tan LH,et al. Cost of Dengue cases in eight countries in the Americas and Asia: a prospective study. Am J Trop Med Hyg 2009;80: 846&#8211;855.
16. Gubler DJ, Clark GG. Dengue/dengue hemorrhagic fever: the emergence of a global health problem. Emerg Infect Dis 1995;1: 55&#8211;57.
17. Koenraadt CJ, Aldstadt J, Kijchalao U, Sithiprasasna R, Getis A, Jones JW et al. Spatial and temporal patterns in pupal and adult production of the dengue vector Aedes aegypti in Kamphaeng Phet, Thailand. Am J Trop Med Hyg 2008;79: 230&#8211;238.
18. Wasay M, Channa R, Jumani M, Zafar A. Changing patterns and outcome of Dengue infection; report from a tertiary care hospital in Pakistan. J Pak Med Assoc 2008;58: 4889.
19. Montenegro D, Lacerda HR, Lira TM, Oliveira DSC, Lima AAF, GuimarĂ£es MJB, et al. Clinical and epidemiological aspects of the dengue epidemic in Recife, PE. Rev Soc Bras Med Trop 2006; 39: 9-13. [DOI via Crossref]    [Pubmed]   
20. Ahmed S, Arif F, Yahya Y, Rehman A, Abbas K, Ashraf S, et al. Dengue fever outbreak in Karachi 2006&#8211;a study of profile and outcome of children under 15 years of age. J Pak Med Assoc 2008;58(1):4-8.
21. Kuo MC, Lu PL, Chang JM, Lin MY, Tsai JJ, Chen YH,et al. Impact of renal failure on the outcome of dengue Viral infection. Clin J Am Soc Nephrol 2008; 3: 1350-6. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
22. Lee IK, Liu JW, Yang KD. Clinical and laboratory characteristics and risk factors for fatality in elderly patients with dengue hemorrhagic fever. Am J Trop Med Hyg 2008; 79: 149-53.

This Article Cited By the following articles

Clinical and laboratory factors associated with mortality in dengue
Trop Doct 2017; 47(2): 141.

1
 
How to Cite this Article
Pubmed Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. Int J Med Sci Public Health. 2013; 2(2): 254-257. doi:10.5455/ijmsph.2013.2.252-255


Web Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. http://www.ijmsph.com/?mno=30840 [Access: August 24, 2019]. doi:10.5455/ijmsph.2013.2.252-255


AMA (American Medical Association) Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. Int J Med Sci Public Health. 2013; 2(2): 254-257. doi:10.5455/ijmsph.2013.2.252-255



Vancouver/ICMJE Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. Int J Med Sci Public Health. (2013), [cited August 24, 2019]; 2(2): 254-257. doi:10.5455/ijmsph.2013.2.252-255



Harvard Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta (2013) Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. Int J Med Sci Public Health, 2 (2), 254-257. doi:10.5455/ijmsph.2013.2.252-255



Turabian Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. 2013. Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. International Journal of Medical Science and Public Health, 2 (2), 254-257. doi:10.5455/ijmsph.2013.2.252-255



Chicago Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. "Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study." International Journal of Medical Science and Public Health 2 (2013), 254-257. doi:10.5455/ijmsph.2013.2.252-255



MLA (The Modern Language Association) Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta. "Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study." International Journal of Medical Science and Public Health 2.2 (2013), 254-257. Print. doi:10.5455/ijmsph.2013.2.252-255



APA (American Psychological Association) Style

Ranadip Chowdhury, Koushik Pan, Anup Sarkar, Subrata Chakrabarti, Tanmay Samanta (2013) Predictors of dengue mortality in a tertiary care hospital at Kolkata: A cross sectional study. International Journal of Medical Science and Public Health, 2 (2), 254-257. doi:10.5455/ijmsph.2013.2.252-255





Most Viewed Articles
  • Management of Appendicular Lump: Early exploration Vs conservative management
    Chandra Prakash Pandey, Ram Chandra Kesharwani, Chandra Gopal Singh Chauhan, Manmohan Krishna Pandey, Purnima Mittra, Pramod Kumar, Arshad Raza
    Int J Med Sci Public Health. 2013; 2(4): 1046-1049
    » Abstract & References » doi: 10.5455/ijmsph.2013.230820131

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Elevated levels of serum uric acid, creatinine or urea in preeclamptic women
    Magna Manjareeka, Sitikantha Nanda
    Int J Med Sci Public Health. 2013; 2(1): 43-47
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.43-47

  • Maternal and fetal outcome in oligohydramnios- Study of 100 cases
    Krishna Jagatia, Nisha Singh, Sachin Patel
    Int J Med Sci Public Health. 2013; 2(3): 724-727
    » Abstract & References » doi: 10.5455/ijmsph.2013.070520132

  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Prevalence and pattern of substance abuse among school childern in nothern India: A rapid assesment study
    Syed Shuja Qadri, RKD Goel, Jagjeet Singh, Surendra Kumar Ahluwalia, Rambha Pathak, Humaira Bashir
    Int J Med Sci Public Health. 2013; 2(2): 273-282
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.271-280

  • Most Downloaded
  • Minor disorder of pregnancy and its home management
    Lata Gururani, Atul Kumar, Gomathi Mahalingam
    Int J Med Sci Public Health. 2016; 5(4): 684-687
    » Abstract & References » doi: 10.5455/ijmsph.2016.03082015111

  • Association between serum ferritin and thyroid hormone profile in hypothyroidism
    Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair
    Int J Med Sci Public Health. 2015; 4(6): 863-865
    » Abstract & References » doi: 10.5455/ijmsph.2015.24012015174

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Effect of sleep deprivation on the attitude and performance of medical students, Riyadh, Saudi Arabia
    Hussein Saad Amin, Ibrahim Salamah Almazroua, Abdullah Sulaiman Alsahlan, Mohammed Abdullah Alrishan, Houssam Mourad Elmourad, Mohammed Mansour Alotaibi, Abdulaziz Ibrahim Almohaisin
    Int J Med Sci Public Health. 2016; 5(3): 575-580
    » Abstract & References » doi: 10.5455/ijmsph.2016.17112015207

  • Management of Appendicular Lump: Early exploration Vs conservative management
    Chandra Prakash Pandey, Ram Chandra Kesharwani, Chandra Gopal Singh Chauhan, Manmohan Krishna Pandey, Purnima Mittra, Pramod Kumar, Arshad Raza
    Int J Med Sci Public Health. 2013; 2(4): 1046-1049
    » Abstract & References » doi: 10.5455/ijmsph.2013.230820131

  • Epidemiology and prevalence of dermatological diseases among schoolchildren of Medak district, Telangana—a clinical survey
    Lakshmi Kumari Villa, Gopi Krishna
    Int J Med Sci Public Health. 2016; 5(7): 1475-1478
    » Abstract & References » doi: 10.5455/ijmsph.2016.28102015238

  • Gunthers with haemolytic anaemia extremly rare: A case report
    Nilesh Kumar, Ankur Varshney, Arvind Anand, Dibyaranjan Behera, Ravi Anand, Ashutosh Tiwari
    Int J Med Sci Public Health. 2013; 2(2): 472-474
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.313-315

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11

  • Most Cited Articles
  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6
    Cited : 25 times [Click to see citing articles]

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11
    Cited : 13 times [Click to see citing articles]

  • Design of fuzzy expert system for diagnosis of cardiac diseases
    Smita Sushil Sikchi , Sushil Sikchi , M S ALI
    Int J Med Sci Public Health. 2013; 2(1): 56-61
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.56-61
    Cited : 9 times [Click to see citing articles]

  • Sugammadex associate persistant bradycardia
    Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu
    Int J Med Sci Public Health. 2014; 3(3): 372-374
    » Abstract & References » doi: 10.5455/ijmsph.2013.251220131
    Cited : 8 times [Click to see citing articles]

  • Migration and health-care access: Barriers to access government health services by migrant tribal community living in an eastern Indian city
    Suchismita Mishra, Yadlapalli S Kusuma, Bontha V Babu
    Int J Med Sci Public Health. 2015; 4(1): 101-108
    » Abstract & References » doi: 10.5455/ijmsph.2015.0110201424
    Cited : 7 times [Click to see citing articles]

  • Clinico-microbiological profile of women with vaginal discharge in a tertiary care hospital of northern India
    Varsha Chaudhary, Ved Prakesh, Kian Agarwal, Vijender Kumar Agrawal, Arun Singh, Sachin Pandey
    Int J Med Sci Public Health. 2012; 1(2): 75-80
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.75-80
    Cited : 6 times [Click to see citing articles]

  • Correlation between obesity and cardio respiratory fitness
    Prabha Setty, BV Padmanabha, BR Doddamani
    Int J Med Sci Public Health. 2013; 2(2): 300-304
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.298-302
    Cited : 6 times [Click to see citing articles]

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42
    Cited : 6 times [Click to see citing articles]

  • Non albicans Candida species: its isolation pattern, species distribution, virulence factors and antifungal susceptibility profile
    Sachin Chandrakant Deorukhkar, Santosh Saini
    Int J Med Sci Public Health. 2013; 2(3): 533-538
    » Abstract & References » doi: 10.5455/ijmsph.2013.080320131
    Cited : 6 times [Click to see citing articles]

  • Initial default among tuberculosis patients diagnosed in selected medical colleges of Puducherry: issues and possible interventions
    Divija Pillai, Anil J Purty, Stalin Prabakaran, Zile Singh, Govindarajan Soundappan, Velavan Anandan
    Int J Med Sci Public Health. 2015; 4(7): 957-960
    » Abstract & References » doi: 10.5455/ijmsph.2015.30012015196
    Cited : 6 times [Click to see citing articles]