E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony.

Cited by (2)

Abstract
Background: Rheumatoid arthritis (RA) is a chronic inflammatory arthritis which can affect extra-articular tissues including eyes.

Objective: This study was aimed to evaluate the ocular manifestations, their correlation with the duration and activity of disease in patients with RA.

Materials and Methods: Patients diagnosed with RA of disease onset age >20 years, irrespective of sex were selected for the study. The eye manifestations were done clinically and also with the help of slit lamp, ophthalmoscope and Schirmer’s test. The findings were statistically analysed.

Result: One hundred cases of RA were selected (mean age 52.54 years). Keratoconjunctivitis sicca was the commonest finding (40%) along with few cases of keratitis (3%), scleritis (1%) and episcleritis (1%). A statistically significant negative correlation was found between the duration of disease and the Schirmer score (r=-0.785; p=0.001). Further, no statistically significant correlation between ocular manifestation and the disease severity were found. Higher ophthalmic involvement was found in seropositive patients.

Conclusion: The commonest ocular manifestation found was keratoconjunctivitis sicca. The frequency and severity of involvement of eyes were found to be significantly associated with the duration of the disease. This emphasizes the need for the routine ophthalmic evaluation of RA patients on a periodic basis for the early detection as well as the prevention of ophthalmic complications and thereby modifying treatment.

Key words: Rheumatoid arthritis, keratoconjunctivitis sicca, episcleritis, keratitis, scleritis


 
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This Article Cited By the following articles

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Can Appropriate Systemic Treatment Help Protect the Cornea in Patients With Rheumatoid Arthritis? A Multidisciplinary Approach to Autoimmune Ocular Involvement
Cornea 2017; (): 1.

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How to Cite this Article
Pubmed Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. Int J Med Sci Public Health. 2017; 6(1): 34-37. doi:10.5455/ijmsph.2016.11062016543


Web Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. http://www.ijmsph.com/?mno=233264 [Access: April 23, 2019]. doi:10.5455/ijmsph.2016.11062016543


AMA (American Medical Association) Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. Int J Med Sci Public Health. 2017; 6(1): 34-37. doi:10.5455/ijmsph.2016.11062016543



Vancouver/ICMJE Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. Int J Med Sci Public Health. (2017), [cited April 23, 2019]; 6(1): 34-37. doi:10.5455/ijmsph.2016.11062016543



Harvard Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony (2017) Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. Int J Med Sci Public Health, 6 (1), 34-37. doi:10.5455/ijmsph.2016.11062016543



Turabian Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. 2017. Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. International Journal of Medical Science and Public Health, 6 (1), 34-37. doi:10.5455/ijmsph.2016.11062016543



Chicago Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. "Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis." International Journal of Medical Science and Public Health 6 (2017), 34-37. doi:10.5455/ijmsph.2016.11062016543



MLA (The Modern Language Association) Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony. "Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis." International Journal of Medical Science and Public Health 6.1 (2017), 34-37. Print. doi:10.5455/ijmsph.2016.11062016543



APA (American Psychological Association) Style

Kezhukkut Jayaraj, Treasa George Alvin, Kakkuzhiyil Skariah Charles, T P Antony (2017) Correlation of ocular manifestations with the duration and activity of disease in patients with rheumatoid arthritis. International Journal of Medical Science and Public Health, 6 (1), 34-37. doi:10.5455/ijmsph.2016.11062016543





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