E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel.

Abstract
Background: Hepatitis C is endemic in most parts of the world. It is a blood borne infection, which has a significant impact in treatment and outcome of renal failure patients undergoing dialysis.

Objective: To determine the seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis in a tertiary care hospital.

Materials and Methods: This study was carried out retrospectively on patients undergoing hemodialysis whose samples were received for Hepatitis C screening in the Department of Microbiology, BJ Medical College, Ahmedabad, Gujarat, India. A total of 910 patients were included in the study conducted over a period of 12 months. Screening for anti-hepatitis C virus (HCV) antibodies was done by a third-generation enzyme-linked immunosorbent assay and their epidemiological data were analyzed.

Result: Of the 910 patients screened for anti-HCV antibodies, 25 patients were found to be positive for Hepatitis C. The overall seroprevalence of hepatitis C among dialysis patients was 2.7%. The HCV positive rates were more among the males and highest in the age group of 30–60 years. Only 44% seropositive patient had raised alanine transaminase level.

Conclusion: Regular screening of hepatitis C patients is mandatory as it has a detrimental effect contributing to morbidity and mortality. Strict adherence to infection control practices should be prioritized in the health-care settings to reduce the burden of disease among the high-risk groups.

Key words: Hepatitis C, hemodialysis, prevalence


 
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How to Cite this Article
Pubmed Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. Int J Med Sci Public Health. 2016; 5(4): 678-680. doi:10.5455/ijmsph.2016.22072015109


Web Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. http://www.ijmsph.com/?mno=197051 [Access: August 24, 2019]. doi:10.5455/ijmsph.2016.22072015109


AMA (American Medical Association) Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. Int J Med Sci Public Health. 2016; 5(4): 678-680. doi:10.5455/ijmsph.2016.22072015109



Vancouver/ICMJE Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. Int J Med Sci Public Health. (2016), [cited August 24, 2019]; 5(4): 678-680. doi:10.5455/ijmsph.2016.22072015109



Harvard Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel (2016) Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. Int J Med Sci Public Health, 5 (4), 678-680. doi:10.5455/ijmsph.2016.22072015109



Turabian Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. 2016. Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. International Journal of Medical Science and Public Health, 5 (4), 678-680. doi:10.5455/ijmsph.2016.22072015109



Chicago Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. "Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India." International Journal of Medical Science and Public Health 5 (2016), 678-680. doi:10.5455/ijmsph.2016.22072015109



MLA (The Modern Language Association) Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel. "Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India." International Journal of Medical Science and Public Health 5.4 (2016), 678-680. Print. doi:10.5455/ijmsph.2016.22072015109



APA (American Psychological Association) Style

Geetha Priyadharsini Subramanian, Mahendra M Vegad, Minesh G Vadsmiya, Sweta M Murawala, Falguni V Patel (2016) Seroprevalence of hepatitis C in renal failure patients on maintenance hemodialysis – Study in a tertiary care hospital – Western India. International Journal of Medical Science and Public Health, 5 (4), 678-680. doi:10.5455/ijmsph.2016.22072015109





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