E-ISSN 2277-338X | ISSN 2320-4664
 

Original Research 


Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital

Archana G Singh, Arvind Lele, Priti Verma.

Abstract
Background: Mother-to-child transmission is the most significant source of infection in children younger than 15 years of age, which can be prevented through an effective package of prevention of parent-to-child transmission (PPTCT) services integrated with the existing reproductive and child health services.

Objective: To determine the seroprevalence and maternal and fetal outcomes in HIV-positive pregnancy.

Materials and Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynecology, NSCB Medical College and Hospital, Jabalpur, Madhya Pradesh, India, from the period of August 1, 2010, to October 31, 2011. All pregnant women who attended antenatal clinic and who came directly to labor ward were counseled for HIV testing. Informed written consent was obtained. The blood samples were collected and tested as per WHO and National AIDS Control Organization (NACO) guidelines. Spouses were counseled and tested. Babies were followed up till 18 months for HIV testing.

Result: Of the 5,332 antenatal registrations, 4,851 (91%) of them were counseled. About 4,804 (99%) consented for HIV testing. The number of women detected as HIV positive was 30. Seroprevalence in our study was 0.62%. The mean age in our study was 24.80 ± 3.22 years. A majority of them were primigravida [15 (50%)]. About 28 (93.3%) spouses were HIV positive and 24 (80%) of them were sexually promiscuous. Around 21 (70%) of them did not practice any contraceptive method. About 20 (87%) women delivered vaginally. Single-dose nevirapine prophylaxis was given to all mother–baby pairs. There were two maternal and two perinatal mortalities.

Conclusion: Married women in childbearing age group are a vulnerable category. The screening of pregnant women, testing, and counseling under PPTCT services through antenatal clinics allows the early identification of HIV infection and provides unique opportunity to implement preventive strategies against HIV infection in women, their infants, and children.

Key words: HIV, mother-to-child transmission, PPTCT, seroprevalence


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Archana G Singh
Articles by Arvind Lele
Articles by Priti Verma
on Google
on Google Scholar
Article Statistics
 Viewed: 2922
Downloaded: 448
Cited: 0


REFERENCES
1. Government of India: National Aids Control Organization. UNGASS Country Progress Report 2008: India. Available at: http:// data.unaids.org/pub/report/india_country_progress_report_en (last accessed on January 29, 2011).
2. Government of India: National AIDS Control Organization (NACO). Annual Report 2010-2011. Available at: http:www. nacoonline.org (last accessed on May 28, 2012).
3. Government of India: Ministry of Health and Family Welfare. Department of AIDS Control, National AIDS Control Organization. Annual Report 2009-10. Available at: http://www.nacoonline.org/ upload/AR202009-10/NACO_ AR_English corrected.pdf (last accessed on November 17, 2010).
4. National Aids Control Organization. Operational Guidelines for Lifelong ART for all Pregnant Women Living with HIV for Prevention of Parent-to-child Transmission (PPTCT) of HIV in India. New Delhi: NACO, December 2013.
5. Indian Council of Medical Research. National Institution of Medical Statistics. National AIDS Control Organization. Technical Report— India HIV—2006. New Delhi: ICMR, 2006.
6. European Collaborative Study. Risk factors for mother-to-child transmission of HIV-1. Lancet 1992;339(8800):1007-12. [DOI via Crossref]   
7. Prevention of parent to child transmission of HIV (PPTCT). Revised Training curriculum participants manual Dec. 2004, Module 2-12.
8. Sebanti G, Parthasarathi C. Epidemiology of HIV in Antenatal women in urban set up. J Obstet Gynecol India 2008;58(2): 134-7.
9. National AIDS Control Organization. Operational Guidelines for Integrated Counseling and Testing Centres. 2007. Available at: http://naco.govt./upload/policies% 20% 20 Guideline/20 website, 20%, operational 20%, Guidelines 20 for % 20 Integrated% 20% counseling 20% and 20% , Testing 20% centres (last accessed on November 18, 2013).
10. Ministry of Health and Family Welfare, NACO. Guidelines for HIV Testing. New Delhi: Ministry of Health and Family Welfare NACO, March 2007. pp. 54-6.
11. Mukherjee S, Ghosh S, Goswami DN, Samanta A. Performance evaluation of PPTCT (Prevention of parent to child transmission of HIV) programme: an experience from West Bengal. Indian J Med Res 2012;136(6):1011-9. [Pubmed]    [PMC Free Fulltext]   
12. Parmeshwari S, Jacob MS, Vijayakumari J, Shalini D, Sushi MK, Sivakumar M. A program on prevention of mother to child transmission of HIV at government hospital, Trichuengode taluk, Namakal district. Indian J Community Med 2009;34(3):261-3. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
13. Mandal S, Bhattacharya RN, Chakraborty M, Pal PP, Roy SG, Mukherjee G. Evaluation of the prevention of parent to child transmission program in a rural tertiary care hospital of West Bengal, India. Indian J Community Med 2010;35(4):491-4. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
14. Dash M, Mohanty I, Sahu S, Narasimham M, Padhi S, Panda P. Declining HIV seroprevalence among pregnant women in South Odisha, India: a six and a half year tertiary care hospital based study. Int J Biomed Adv Res 2012;3(7):546-51. [DOI via Crossref]   
15. Sinha A, Roy M. An ICMR task force study of prevention of parent to child transmission (PPTCT) service delivery in India. Indian J Public Health 2008;52(4):200-2. [Pubmed]   
16. Joshi U, Kadri A, Bhojiya S. Prevention of parent to child transmission services and interventions—coverage and utilization: a cohort analysis in Gujarat, India. Indian J Sex Transm Dis 2010;31(2):92-8. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
17. Snehamay C, Sudipta B, Arunansu T, Sankar GU. Seroprevalence and utilization of therapeutic interventions in PPTCT services in a teaching hospital in Kolkata. J Obstet Gynecol India 2007;57(3):251-6.
18. Ukey PM, Akulwar SL, Powar RM. Seroprevalence of immunodeficiency virus infection in pregnancy in a tertiary care hospital. Indian J Med Sci 2005;59(9):382-7. [DOI via Crossref]    [Pubmed]   
19. Gupta S, Gupta R, Singh S. Seroprevalence in HIV in pregnant women in North India: a tertiary care hospital based study BMC Infect Dis 2007;7:133. [DOI via Crossref]    [Pubmed]    [PMC Free Fulltext]   
20. Mathur M, Taklikar S, Turbadkar D. Study of HIV seroprevalence and sociodemographic patterns in antenatal cases and vertical transmission to neonates. Indian J Microbiol 2008;26(3):289-90. [DOI via Crossref]   
21. World Health Organization. Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection, Recommendations for a Public Health Approach. Geneva: WHO, June 2013.
22. National Aids Control Organization. Updated Guidelines for Prevention of Parent-to-Child Transmission (PPTCT) of HIV using Multidrug Anti-retroviral Regimen in India. New Delhi: Ministry of Health and Family Welfare, December 2013.
23. WHO Rapid advise : Use of antiretroviral drugs for treating pregnant women and preventing HIV infections in infants. Nov. 30, 2009. Available at: http://www.who.int/hiv/pub/mtct/advice/en/ index.html.

How to Cite this Article
Pubmed Style

Archana G Singh, Arvind Lele, Priti Verma. Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. Int J Med Sci Public Health. 2015; 4(12): 1750-1754. doi:10.5455/ijmsph.2015.30052015361


Web Style

Archana G Singh, Arvind Lele, Priti Verma. Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. http://www.ijmsph.com/?mno=189982 [Access: October 18, 2019]. doi:10.5455/ijmsph.2015.30052015361


AMA (American Medical Association) Style

Archana G Singh, Arvind Lele, Priti Verma. Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. Int J Med Sci Public Health. 2015; 4(12): 1750-1754. doi:10.5455/ijmsph.2015.30052015361



Vancouver/ICMJE Style

Archana G Singh, Arvind Lele, Priti Verma. Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. Int J Med Sci Public Health. (2015), [cited October 18, 2019]; 4(12): 1750-1754. doi:10.5455/ijmsph.2015.30052015361



Harvard Style

Archana G Singh, Arvind Lele, Priti Verma (2015) Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. Int J Med Sci Public Health, 4 (12), 1750-1754. doi:10.5455/ijmsph.2015.30052015361



Turabian Style

Archana G Singh, Arvind Lele, Priti Verma. 2015. Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. International Journal of Medical Science and Public Health, 4 (12), 1750-1754. doi:10.5455/ijmsph.2015.30052015361



Chicago Style

Archana G Singh, Arvind Lele, Priti Verma. "Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital." International Journal of Medical Science and Public Health 4 (2015), 1750-1754. doi:10.5455/ijmsph.2015.30052015361



MLA (The Modern Language Association) Style

Archana G Singh, Arvind Lele, Priti Verma. "Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital." International Journal of Medical Science and Public Health 4.12 (2015), 1750-1754. Print. doi:10.5455/ijmsph.2015.30052015361



APA (American Psychological Association) Style

Archana G Singh, Arvind Lele, Priti Verma (2015) Evaluation of HIV-positive pregnancy in a tertiary-care referral hospital. International Journal of Medical Science and Public Health, 4 (12), 1750-1754. doi:10.5455/ijmsph.2015.30052015361





Most Viewed Articles
  • Management of Appendicular Lump: Early exploration Vs conservative management
    Chandra Prakash Pandey, Ram Chandra Kesharwani, Chandra Gopal Singh Chauhan, Manmohan Krishna Pandey, Purnima Mittra, Pramod Kumar, Arshad Raza
    Int J Med Sci Public Health. 2013; 2(4): 1046-1049
    » Abstract & References » doi: 10.5455/ijmsph.2013.230820131

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Elevated levels of serum uric acid, creatinine or urea in preeclamptic women
    Magna Manjareeka, Sitikantha Nanda
    Int J Med Sci Public Health. 2013; 2(1): 43-47
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.43-47

  • Maternal and fetal outcome in oligohydramnios- Study of 100 cases
    Krishna Jagatia, Nisha Singh, Sachin Patel
    Int J Med Sci Public Health. 2013; 2(3): 724-727
    » Abstract & References » doi: 10.5455/ijmsph.2013.070520132

  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6

  • Knowledge, Attitude, and Practices (KAP) study on HIV / AIDS among HIV patients, care givers and general population in north-eastern part of India.
    L P Meena, S K Pandey, M Rai, Anju Bharti, Shyam Sunder
    Int J Med Sci Public Health. 2013; 2(1): 36-42
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.36-42

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Prevalence and pattern of substance abuse among school childern in nothern India: A rapid assesment study
    Syed Shuja Qadri, RKD Goel, Jagjeet Singh, Surendra Kumar Ahluwalia, Rambha Pathak, Humaira Bashir
    Int J Med Sci Public Health. 2013; 2(2): 273-282
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.271-280

  • Most Downloaded
  • Minor disorder of pregnancy and its home management
    Lata Gururani, Atul Kumar, Gomathi Mahalingam
    Int J Med Sci Public Health. 2016; 5(4): 684-687
    » Abstract & References » doi: 10.5455/ijmsph.2016.03082015111

  • Association between serum ferritin and thyroid hormone profile in hypothyroidism
    Ashuma Sachdeva, Veena Singh, Isha Malik, Prasanta Saha Roy, Himanshu Madaan, Rajesh Nair
    Int J Med Sci Public Health. 2015; 4(6): 863-865
    » Abstract & References » doi: 10.5455/ijmsph.2015.24012015174

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142

  • Effect of sleep deprivation on the attitude and performance of medical students, Riyadh, Saudi Arabia
    Hussein Saad Amin, Ibrahim Salamah Almazroua, Abdullah Sulaiman Alsahlan, Mohammed Abdullah Alrishan, Houssam Mourad Elmourad, Mohammed Mansour Alotaibi, Abdulaziz Ibrahim Almohaisin
    Int J Med Sci Public Health. 2016; 5(3): 575-580
    » Abstract & References » doi: 10.5455/ijmsph.2016.17112015207

  • Management of Appendicular Lump: Early exploration Vs conservative management
    Chandra Prakash Pandey, Ram Chandra Kesharwani, Chandra Gopal Singh Chauhan, Manmohan Krishna Pandey, Purnima Mittra, Pramod Kumar, Arshad Raza
    Int J Med Sci Public Health. 2013; 2(4): 1046-1049
    » Abstract & References » doi: 10.5455/ijmsph.2013.230820131

  • Epidemiology and prevalence of dermatological diseases among schoolchildren of Medak district, Telangana—a clinical survey
    Lakshmi Kumari Villa, Gopi Krishna
    Int J Med Sci Public Health. 2016; 5(7): 1475-1478
    » Abstract & References » doi: 10.5455/ijmsph.2016.28102015238

  • Diabetic nephropathy: Progression and pathophysiology
    Deepak N Parchwani, Amit A Upadhyah
    Int J Med Sci Public Health. 2012; 1(2): 59-70
    » Abstract & References » doi: 10.5455/ijmsph.2012.1.59-70

  • Gunthers with haemolytic anaemia extremly rare: A case report
    Nilesh Kumar, Ankur Varshney, Arvind Anand, Dibyaranjan Behera, Ravi Anand, Ashutosh Tiwari
    Int J Med Sci Public Health. 2013; 2(2): 472-474
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.313-315

  • Patient satisfaction about health care services: A cross sectional study of patients who visit the outpatient department of a civil hospital at Surendranagar, Gujarat
    Krupal Joshi, Kishor Sochaliya, Shyamal Purani, Girija Kartha
    Int J Med Sci Public Health. 2013; 2(3): 659-663
    » Abstract & References » doi: 10.5455/ijmsph.2013.250420131

  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6

  • Most Cited Articles
  • Zinc: The trace element of major importance in human nutrition and health
    Jayant D Deshpande, Mohini M Joshi, Purushottam A Giri
    Int J Med Sci Public Health. 2013; 2(1): 1-6
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.1-6
    Cited : 27 times [Click to see citing articles]

  • Burden of non communicable diseases in India: Setting priority for action
    Kalpa Sharma
    Int J Med Sci Public Health. 2013; 2(1): 7-11
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.7-11
    Cited : 16 times [Click to see citing articles]

  • Sugammadex associate persistant bradycardia
    Murat Bilgi, Abdullah Demirhan, Akcan Akkaya, Umit Yasar Tekelioglu, Hasan Kocoglu
    Int J Med Sci Public Health. 2014; 3(3): 372-374
    » Abstract & References » doi: 10.5455/ijmsph.2013.251220131
    Cited : 9 times [Click to see citing articles]

  • Design of fuzzy expert system for diagnosis of cardiac diseases
    Smita Sushil Sikchi , Sushil Sikchi , M S ALI
    Int J Med Sci Public Health. 2013; 2(1): 56-61
    » Abstract & References » doi: 10.5455/ijmsph.2013.2.56-61
    Cited : 9 times [Click to see citing articles]

  • Internet addiction among professional courses students: A study from central India
    Arvind Sharma, Rupesh Sahu, Pradeep Kumar Kasar, Richa Sharma
    Int J Med Sci Public Health. 2014; 3(9): 1069-1073
    » Abstract & References » doi: 10.5455/ijmsph.2014.180620142
    Cited : 8 times [Click to see citing articles]

  • Abdominal volume index and conicity index in predicting metabolic abnormalities in young women of different socioeconomic class
    Vikram Gowda, Kripa Mariyam Philip
    Int J Med Sci Public Health. 2016; 5(7): 1452-1456
    » Abstract & References » doi: 10.5455/ijmsph.2016.13102015231
    Cited : 8 times [Click to see citing articles]

  • Migration and health-care access: Barriers to access government health services by migrant tribal community living in an eastern Indian city
    Suchismita Mishra, Yadlapalli S Kusuma, Bontha V Babu
    Int J Med Sci Public Health. 2015; 4(1): 101-108
    » Abstract & References » doi: 10.5455/ijmsph.2015.0110201424
    Cited : 7 times [Click to see citing articles]

  • Non albicans Candida species: its isolation pattern, species distribution, virulence factors and antifungal susceptibility profile
    Sachin Chandrakant Deorukhkar, Santosh Saini
    Int J Med Sci Public Health. 2013; 2(3): 533-538
    » Abstract & References » doi: 10.5455/ijmsph.2013.080320131
    Cited : 7 times [Click to see citing articles]

  • Prevalence and clinical characteristics of autism spectrum disorders in school-age children in Taif- KSA
    Ali H.S Al-Zahrani
    Int J Med Sci Public Health. 2013; 2(3): 578-582
    » Abstract & References » doi: 10.5455/ijmsph.2013.160420133
    Cited : 7 times [Click to see citing articles]

  • A study on the prevalence of refractive errors among school childern of 7-15 years age group in the field practice areas of a medical college in bangalore
    Pavithra MB, Maheshwaran R, Rani Sujatha MA
    Int J Med Sci Public Health. 2013; 2(3): 641-645
    » Abstract & References » doi: 10.5455/ijmsph.2013.220420131
    Cited : 7 times [Click to see citing articles]